Summary: Fasoracetam is a newer addition to the racetam family. It’s a nootropic that helps in relieving anxiety, enhancing memory, and improving overall cognition.
Fasoracetam is a promising and exciting addition to the racetam family. It’s reported to have the ability to enhance memory and cognition while relieving depression and anxiety. Additionally, it also has a potential for treating ADHD symptoms. Even though Fasoracetam is a new name on the nootropic scene, it was developed by a Japanese pharmaceutical company more than 20 years ago as a potential treatment for vascular dementia. However, it was put on hiatus after a failed trial. The clinical data were then bought by NeuroFix in 2013. Clinical trials began in 2016 with its focus on treating ADHD symptoms in children. The experiments have shown a great promise as a potential ADHD treatment. In 2016, the FDA accepted the substance for evaluation.
Fasoracetam is a research chemical of the racetam family. It is a putative nootropic that failed to show sufficient efficacy in clinical trials for vascular dementia. It is currently being studied for its potential use for attention deficit hyperactivity disorder.Wikipedia
Benefits & Effects
Fasoracetam Improves Memory Cognition
Fasoracetam minimizes memory decline, forgetfulness, and amnesia. Individuals who use it report it positively impacts their memory. That is due to the chemical that it produces, which increases learning, memory and cognitive functions. (R)
Fasoracetam Relieves Anxiety and Depression
Fasoracetam relieves anxiety, improves mood, and eases depression by acting on glutamate and gamma-aminobutyric acid (GABA). By up-regulating GABA and suppressing the excess production of the excitatory neurotransmitter glutamate, Fasoracetam offers a non-jittery and smooth feeling of calmness, relaxation and improved mood. (R) (R)
Potential ADHD Treatment
A study on 30 individuals ranging between 12 to 17 years old test the impact of Fasoracetam on ADHD patients. The subjects were receiving fasoracetam for five weeks, after which improvements were observed relating to ADHD symptoms. (R)
Increases Creativity and Motivation
With more research done on Fasoracetam, the improvement in creativity and motivation progresses as well. Many users report that not only it makes them inspired by nature but keeps them motivated too. These self-reports are credible for boosting moods and ability to increase the release and production of the neurotransmitter acetylcholine which is responsible for cognition and learning.
Mechanism of Action
How Does Fasoracetam Work?
There is no clear evidence to support how it works to improve cognition. The theories that exist that describe that it as an interaction with the receptors of glutamate and GABA and the cholinergic system. Fasoracetam works of a specific group of glutamate receptors known as metabotropic glutamate receptors, which play multiple roles in the brain and body mainly relating to memory, learning, and anxiety. In increasing acetylcholine fasoracetam is a powerful cholinergic, significantly increasing the uptake of choline in the cortex and hippocampus. The brain uses the additional choline to produce more acetylcholine, the neurotransmitter most strongly associated with learning, memory, and overall cognition.
How to Take Fasoracetam?
Given that it is produced 20mg dosage, 20mg would be a good starting point. Anecdotal reports suggest smaller doses of 15 to 30mg per day, while dosages used in clinical trials for ADHD were 100, 200, and 400mg twice a day.
Personally I tried anywhere from 20mg per dose to 60 mg per dose. The difference was barely notable.
As always, pair it with Alpha GPC or any choline source to potentiate the effect and prevent a headache.
What Are Fasoracetam Side Effects?
Fasoracetam is safe when taken responsibly. The most common side effect, similar to all racetams, including fatigue, headache, and digestive discomfort.
The is no scientific evidence available on the specific interactions between other drugs and fasoracetam.
Here is an on-going discussion thread on Reddit’s stack advice regarding Fasoracetam usage that is packed with both information on the nootropic, as well as different user experiences (myself included), suggestions, and thoughts on the nootropic:
Some of the interesting & diverse comments from that thread:
Not from me, unfortunately. Made me feel worse. I’ve lost any faith in common nootropics because they do nothing for me.Oxetine
10-20mg gave me near instantaneous relief from anxiety—sublingual that is.tawatson2
While it seemed to help somewhat with anxiety (not a magic bullet) I also felt like some cognitive abilities were actually reduced by it. I had problems carrying out my work with usual performance and with internalizing new tasks. Sometimes you can’t judge if a nootropic really helps much of anything at all but in case of fasoracetam the downsides seemed pronounced enough for me not to continue.sheldonopolis
Fasoracetam is a new nootropic but has had numerous experiments done on it. However, it has already developed a strong force in the nootropic community. Many people find it an excellent choice to relieve anxiety and depression. Some people also say that it helps in cognition, clarity, and focus. It works well when used responsibly.