what are nootropics? nootropics information

Everything you need to know about nootropics: what they are, what they do, the science, as well as how to find the best nootropic for your own personal needs.

Aside from the idea emerging from Mr. Bradley Cooper when filming Limitless, let's try to get an understanding of what nootropics actually are – in a way to make me and the world forget about the Netflix series attempt of reproducing it.

There are so many people out there who have no clue whatsoever what are Nootropics and whether do Nootropics work or not. And there are also many who would immediately ask, are Nootropics legal?

Here we are going to try and answer all the questions you have and help you get a better insight into this fantastic – yet risky to an extent – world of cognitive enhancers, nootropics, and smart drugs. Whatever you choose to call them.

Nootropics (which are often referred to as “smart drugs,” cognitive enhancers, and intelligence enhancers, to name a few) are drugs, supplements, and functional and super-foods that improve brain overall functions. They boost cognition, memory, intelligence, motivation, attention, and concentration.

Nootropics work by modulating neuronal metabolism, cerebral oxygenation, neurotransmitter availability, increasing neurotrophic factors and by affecting other cellular processes. If you’re wondering about the mechanism of work, you can visit any of the pages, for example, click on Mechanism of Action and it will redirect you to the Acetyl L-Carnitine page, in which section #3 explains the exact way that nootropic works within our body…or brains. Each nootropic has a different way of working, which is called mechanism of work. Moreover, nootropics on their separate pages have a benefits and effects section as well as a ‘how it works,’ in which each is addressed.

  • Enhance learning
  • Resist impairing agents
  • Improve resistance to the brain “aggression.”
  • Facilitate interhemispheric transfers of information
  • Increase tonic, cortico-subcortical “control.”
  • Not have the usual pharmacological effects of neuro-psychotropic drugs.

Depending on the effect you seek. For example, a person who looking to increase their learning capability would be looking for a different nootropic than a person seeking to improve their memory. Generally speaking, the most popular ones are:

In general, yes, most nootropics are legal. However, some are unregulated, some are unregistered, and some are straight up illegal. It depends a lot on where you live, which country, and which state or city.

Nootropics Information

Nootropics Wiki 💡​

What Are Racetams?

For a more comprehensive FAQ please visit the Ultimate Nootropics Frequently Asked Questions page by following this link. If you have any questions you need to have answered or think are worth adding to the list below, please do get in touch with us!

What Are Racetams?

Racetams are a category of synthetic nootropics and medications grouped due to sharing the same chemical structure. Therefore; producing similar effects. They vary when it comes to exact structure, strength, dosage, and concentration. However, fundamentally have impacts on the brain in similar ways that support their shared  chemical composition. They are admired for their abilities to make the brain work much more effectively, essentially boosting memory, expanding learning capacity, promoting focus, boosting energy –in addition to providing an overall boost to brain function. The synthetic nootropic – and also the substance that  led the scientist C.E. Giurgea to coin the term “nootropic” and formulate this class of cognitive enhancers originally was Piracetam. All popular racetams currently derive from Piracetam, although some are much more potent.

What Are The Most Popular Racetams?

How Do Racetams Work?

Racetams work by affecting the assembly of the neurochemical neurotransmitter. Some work by boosting the functioning of the neurotransmitter receptors, whereas others improve the output of the neurochemical and impede the breakdown of neurotransmitter. Every one of those actions will immensely enhance the body’s cholinergic system. The brain takes choline and turns it into neurotransmitter, and whereas scientists  admit they don’t perceive neurotransmitter nonetheless, they understand enough to grasp that the brain uses it for everything from learning and focus to decision-making, memory, and alternative cognitive actions.

Racetams additionally facilitate the quantity of gas, glucose, and nutrients traveling from your blood to the brain, giving your mind additional fuel. Improved aldohexose metabolism  helps to extend concentration, focus, and need. By boosting neurotransmitter and aldohexose metabolism, racetams are potent tools to add in your nootropic stack. Acetylcholine plays a dominant role within the brain, liable for memory formation, attention, and thinking, further as alternative crucial psychological feature functions.

What Are the Best Racetams Available?

Since the invention of Piracetam, there have been 19 different derivatives to date. Not all  are nootropics; some are in use for entirely different and medical reasons.

The first standard racetams in alphabetical order are Aniracetam, Oxiracetam, Phenylpiracetam, Piracetam, Pramiracetam, and although not exactly a racetam per say, it nevertheless should be in the list; Noopept. Although it’s not technically a racetam, Noopept works in a very similar way to this group, enough to be counting as one.

While all of those racetams operate somewhat equally, they are doing have some structural variations. Some facilitate to spice up focus, others to assist producers, some stimulate (but not within the same method as a stimulant), whereas others calm or alleviate anxiety.
The newer additions to the racetam family are Fasoracetam, Coluracetam, and Sunifiram.

Are Racetams Safe?

Many people believe that since racetams are synthetic, they are not safe. That is an assumption without scientific evidence. The facts and numerous studies publicly available at The National Center for Biotechnology Information show that racetams are very reliable; despite various analysis attempting to prove them unsafe. Were they able to confirm they are toxic, it would burst within the medical field leading to limited usage.

The facts and studies from the very invention of them and up to date fail to do so. Most of the negativity around their use comes from anecdotal reports, which have their benefit. However, don’t seem to be a reliable supply of data. Needless to mention: it is vital to start out small, and lookout for adverse effects that may occur.

The possibilities of side effects with racetams are usually headaches,  brain fog, and sleep disturbances. These are very rare, nevertheless, possible. The most effective way to avoid side effects is to add a choline source such as Alpha GPC. Build  up the dose gradually, allowing the body to adapt to it.

What Are Racetams Side Effects?

Racetams are considered to be safe, and yield low toxicity. However, as with all nootropics, you should be aware of the potential side-effects of racetams, not just the actual side effects. Side-effects for racetams are rare and mild, if any. Most of which occur when an individual do not stick to the recommended dosage, or decide to go on “megadosing” without prior knowledge, then they are more likely to get some unwanted or adverse effects.

Most common racetam side-effects are: headache, nausea, trouble getting to sleep, and irritability. If you are experiencing this symptoms, simply stop taking your racetams. Before continuing, discuss usage with your doctor.

Note: Headaches can generally be counteracted or prevented when taking your racetam with a choline source.

How to Take Racetams?

When it comes to dosage or method of administration, each racetam has its different guidelines. Some are recommended to be taken once a day only while some others twice or thrice. Below is the recommended dosage for each racetam.

How to Take Pramiracetam?

A total daily intake of 1200 mg pramiracetam is optimal, split into two 600 mg or three 400 mg doses throughout the day.

This is the lowest effective dose. On an individual level, it should be adjusted as required to accomplishing the desired effect.

How to Take Sunifiram?

Sunifiram works effectively at a dosage of 5 to 10 mg – at a maximum of three times per day. This the safe dose which has to be taken sublingually for maximum efficacy and absorption.

It is advised that one starts with the smallest doses to prevent side effects and toxicity. Although it is not in documentation, tolerance can grow with excessive usage, so it is better to take it occasionally instead of daily basis.

How to Take Fasoracetam?

Given that it is produced 20mg dosage, 20mg would be a good starting point. Anecdotal reports suggest smaller doses of 15 to 30mg per day, while dosages used in clinical trials for ADHD were 100, 200, and 400mg twice a day.

Personally I tried anywhere from 20mg per dose to 60 mg per dose. The difference was barely notable.

As always, pair it with Alpha GPC or any choline source to potentiate the effect and prevent a headache.

How to Take Coluracetam?

The recommended starting dose is 20mg due to that being the manufactured one. 

There are claims that researchers testing coluracetam dosage of 240 mg per day are finding no side effects. However, the source link to that claim is broken.

My Personal Experience: the maximum I’ve taken is 60mg in single dose. It caused me a slight headache and yield no special outcome.

How To Take Oxiracetam?

Oxiracetam average dose is 1,200-2,400mg taken in 2 or 3 even doses throughout the day. An example would be:
– 2x 800mg per day or
– 3x 400mg per day

How To Take Phenylpiracetam?

The usual dose are between 100-200 mg per dose, up to two or three times a day. However, I prefer taking a 200mg dose once only. The effects are much more present and pleasing.

Tolerance to Phenylpiracetam builds up quickly. Therefore, minimize your use to when you need it rather than making it a part of a daily stack.

How to Take Aniracetam?

Aniracetam has a short half-life of about 1 to 3 hours. Therefore, many users advice to take it in 2 to 3 doses throughout the day to prolong the effect.

I only take one 750 mg dose in the morning and am satisfied with this regime.

Aniracetam powder form is also available, though not as in favor as the capsule form due to its strong, bitter taste.

The recommended as well as typical dosage is 750 to 1500 mg, subjective to the individual.
Taking smaller doses of as little as 400 mg has been found to be effective. Hence, it is wise to start at the lowest effective dose and build up from there as desired.

How To Take Piracetam?

The typical dose for adults is between 1,200 to 4,800 mg a day.

The most notable effective dose is 1,600 mg, taken three times a day, making a total of 4,800 mg per day.

You can always check and get more information on racetams on reddit.

Return To Nootropics Information Homepage

  1. What Are Nootropics?

    The original definition of nootropics when the term was coined, was this: “Nootropics (often called things like cognitive enhancers, smart drugs, brain boosters, etc) are supplements, drugs, super-foods that improve brain functions. They boost cognition, memory, intelligence, motivation, attention, and concentration.” However, the term gradually expanded to mean cognitive enhancers with little-to-no side effects and toxicity.

  2. What Differentiates Nootropics from other Supplements?

    To be recognized as a “Nootropic”, a supplement has to meet certain standards. Those standards are:

    Enhances learning
    Improves resistance to the brain
    Facilitate hemispherical transfers of information
    Increase tonic, cortico-subcortical “control.”
    Not have the usual pharmacological effects of neuro-psychotropic drugs.

  3. What Are Cognitive Enhancers?

    A cognitive enhancer is defined by its ability to augment performance on one or more cognitive measures. The term refer to a wide range of natural and artificial compounds which enhance cognitive function.

  4. What is Neuroprotection?

    Neuroprotection refers to the mechanisms and strategies used to protect against nerve injury or degeneration and to prevent the breakdown of the central nervous system. More about it here.

  5. Are Nootropics Safe?

    Yes. Nootropics are safe. However, today, the word nootropics is not as exclusive as it used to be as when first discovered. Although they are safe, that should not be sufficient for you to assume any product you buy is going to be safe just because it says the word nootropic on it.

  6. What Determines the Safety of Nootropics?

    Where you buy your nootropics from, and the legitimacy of the manufacturer our individual body's reaction to it.

  7. Are Nootropics Addictive?

    No. Nootropics are not addictive. If they were addictive, they wouldn’t qualify, nor meet the standards, to sell as nootropics. Therefore its crucial that you find the right company and search what other people are saying about it to ensure ingredient quality and purity. That said, it does not mean there aren’t cases of people who are addicted to nootropics. But those cases are quite complex and unusual. More often than not, they are due to abuse and consumption of very high doses, often called “megadose”. It is common to see addiction and withdrawal discussions especially when it comes to nootropics like Phenibut. In fact, there is an entire subreddit dedicated to Phenibut quitting. So when asking this question you have to first understand what is addiction.

  8. What Is Addiction?

    There are two types of addiction when speaking of substance addiction and abuse:
    Physical Addiction: which is the condition in which the body has developed a physical dependency, due to chronic use and/or abuse, of a tolerance-forming substance.
    Psychological Addiction: which is the condition in which a person develops a mental dependency, often due to abuse and repetition, to a certain substance.
    Both dependencies only occur as a result of an individual’s use of a substance. Therefore, the answer to this question is that: nootropics are not addictive, but they can be when abused.

  9. Are Nootropics Legal?

    By definition, yes. Nootropics are legal. In fact, it is one of the standards for a substance to meet, in order to be universally acknowledged as a Nootropic. However, we all know that only few companies still go with that definition of what makes a nootropic, and therefore, there is almost always a legality questions coming up, and often risk involved, in the process of purchasing nootropics online. Especially when living in a country or city with strict importing and exporting laws.

  10. How Do Nootropics Work?

    Each nootropic has a different way of working, which is called mechanism of work. Moreover, nootropics on their separate pages have a benefits and effects section as well as a ‘how it works,’ in which each is addressed. Nootropics work by modulating neuronal metabolism, cerebral oxygenation, neurotransmitter availability, increasing neurotrophic factors and by affecting other cellular processes. If you’re wondering about the mechanism of work, you can visit any of the pages, for example, click on Mechanism of Action and it will redirect you to the Acetyl L-Carnitine page, in which section #3 explains the exact way that nootropic works within our body…or brains.

  11. What Are the Best Nootropics?

    Depending on the effect you seek. For example, a person who looking to increase their learning capability would be looking for a different nootropic than a person seeking to improve their memory. You should choose what to supplement with based on what you want to achieve as well as improve. Some of the popular outcomes people look for are anxiety treatment, energy, focus, concentration, increasing learning capacity, increasing memory recall, physical performance, enhancing mood, creativity. It is essential to research before you make a purchase though keep in mind that customer reviews are subjective. Each person reacts differently to a particular nootropic. Some of the classic ones that I felt every single one of them consciously:

  12. How Long Do Nootropics Take to Work?

    It totally depends on the particular nootropic. Some start to work quickly. The effects can be felt in anywhere from 20 minutes to an hour. Others need to build up in the body over the course of several weeks to reach optimal concentrations.

  13. Where Can I Buy Nootropics From?

    There are many options online when considering buying nootropics. However, you have to be careful as there are just as many scam vendors. There are many cases where vendors are scamming customers by adding a particular irrelevant or illegal substance and mixing the product in a way to sell partly pure orders to maximize their profit. Research the manufacturer’s credibility, and read customers experiences & reviews from members within nootropics communities such as Reddit’s /nootropics sub.

  14. Where can I buy Nootropics in Dubai, UAE?

  15. What is Acetyl L-Carnitine (ALCAR)?

    Acetyl L-Carnitine (also known as ALCAR) is a multi-functional nutrient nootropic that benefits the body and brain. A potent antioxidant and neuroprotectant, it is a powerful nootropic that promotes energy and longevity. It works synergies very well with other nootropics and usually is a primary component in most nootropic stacks.

  16. What is Alpha-GPC?

    A natural choline compound, Alpha-GPC works on its own as a powerful memory booster, and in combination with other nootropics a powerful potentiator notably boosting cognitive enhancement. It’s used for cognitive-promoting qualities, as well as to increase energy and power output during weight-lifting or exercising.

  17. What is Adrafinil?

    Adrafinil is a stimulating nootropic that provides remarkable nootropic properties. It metabolizes into the famous Modafinil, making it a smart tool for enduring in longer, mentally demanding tasks.

  18. What is Ashwagandha?

    Ashwagandha is an ancient herb often referenced to as “the king of Ayurvedic medicine.” Its favorable effect remains the ability to reduce and often diminish stress and different types of anxiety. Many would even refer to it as the “stress eliminator.”

    Additionally, Ashwagandha provides neuroprotection and currently under clinical trials.

  19. What is Bacopa Monnieri?

    Bacopa monnieri is a powerful natural herb nootropic used for ages for its memory enhancing and anti-aging effects. It reduces anxiety and improves memory formation. It also expands learning capacity, decreases stress and even offers neuroprotection.

  20. What is Coluracetam?

    Coluracetam is a less known member of the racetam family of nootropics. In combination with the common cognitive enhancement of racetams, early scientific trials confirm that it is beneficial in the treatment of Major Depressive Disorder as well as with Generalized Anxiety, in addition to its nootropic features.

  21. What is L-Theanine?

    L-theanine is a natural amino acid existing almost only in green tea leaves. It works brilliantly in unwinding and relaxing the body and brain without causing drowsiness, while reducing stress and increasing cognitive function. Due to not causing drowsiness, it is the perfect choice to combine with stimulants of any sort to take the edge off.

  22. What is N-Acetyl L-Tyrosine (NALT)?

    N-Acetyl L-Tyrosine (NALT) is a more bioavailable form of Tyrosine, an amino acid that’s also a nootropic. It improves mood, memory, and enhances cognitive abilities in many ways. It has great effects of reducing stress and maintaining mental performance during sleep deprivation.

  23. What is Phenylpiracetam?

    Phenylpiracetam is a potent and fast-acting smart drug of the racetam family. It enhances cognitive abilities as well as boosts physical strength. The Olympics Anti-Doping committee bans it for being too stimulating for athletes.

  24. What is Noopept?

    Noopept is one of the most potent nootropics on the market today. It provides an overall cognition boost along with a small psychostimulatory effect. Unlike many nootropics, noopept effects kick in within minutes of consumption, making it an attractive choice when facing mentally demanding tasks.

  25. What is Pramiracetam?

    Pramiracetam is gaining high attention after a study showing an outstanding success rate of 96% in reversing amnesia, surpassing the one it actually derived from, piracetam. It boosts cognition and improves memory, increases concentration, learning capacity, and furthermore promotes and assists in maintaining and enduring prolonged periods of focus.

  26. What is Oxiracetam?

    Oxiracetam is one of the most valuable racetam class nootropics. Its ability to boost productivity and problem-solving has made it a favorite – and a best seller.

  27. What is Lion’s Mane Mushroom?

    Lion’s Mane Mushroom has become one of nature’s most potent nootropic supplement for the brain. There is evidence that is can permanently enhance brain function as well as protect the brain and promote NGF and neurogenesis.

  28. What is Rhodiola Rosea?

    Rhodiola Rosea is a naturally growing flower plant from the wild Arctic regions of Europe, widely used in Chinese, Scandinavian and Russian traditional medicine. It is believed to be the perfect remedy for fatigue and burnouts. Moreover, Rhodiola is useful for the brain; protecting it from toxin damage as well as boosting memory and…

  29. What is Modafinil?

    Modafinil is a powerful stimulant that promotes ‘wakefulness’ and treats sleep disorders. It prevents daytime sleepiness and fatigue, as well as offering nootropical benefits such as enhancing mood, increasing mental alertness, increasing motivation, improving reaction time, reducing fatigue, and even enhancing memory.

  30. What is Sunifiram?

    Sunifiram is a potent and powerful nootropic that enhances memory, expands learning capacity, and uplifts mood. A recent addition to the racetam family that seems more than promising.

  31. What is Fasoracetam?

    Fasoracetam is a newer addition to the racetam family. It’s a nootropic that helps in relieving anxiety, enhancing memory, and improving overall cognition.

  32. What is Aniracetam?

    Aniracetam (my go-to racetam), is a multipurpose nootropic providing benefits in several different areas. It produces remarkable anxiolytic effects, thereby improving cognition and enhancing mood. It also sharpens focus, increases verbal fluency, information processing, as well as expands the brain’s capability allowing greater information processing.

  33. What is Piracetam?

    Piracetam is a nootropic designed to enhance brain function. It's the primary compound in the racetam family, from which almost 20 different derivatives have been discovered to date. It’s a revolutionizing nootropic that improves memory and remarkably boosts cognitive function.

  34. What is Phenibut?

    Phenibut is one of the best selling nootropics today. As a GABAergic agent, it works on the GABA neurotransmitter distinctly reducing anxiety. It also lessens depression, and PTSD symptoms, improving sleep, and providing an overall feeling of ease and well-being.

  35. Do Nootropics Show Up on Drug Tests?

    No, they shouldn’t. But false positives do happen. A false positive is when a drug screen comes back positive for something that was never taken. Drug screens don’t test for the drugs directly. They test for the metabolites that drugs break down into in the body. Sometimes unrelated drugs break down into similar metabolites causing a false reading. Common drugs screens do not look for nootropics. Standard 5-panel drug screens (commonly used for employment) only test for THC, PCP, cocaine, amphetamines, and opiates. 

    Nootropics should not cause a false positive for any of these things. However, it’s always possible. If you have to undergo extensive drug testing, it is recommended that you use caution. And it should also be noted that amphetamines (Adderall, Vyvanse, Dexedrine, etc.) will show up on a standard drug screen. If you have a prescription for one of these medications, then it should not be a problem. Otherwise, you should not take any drugs containing any amphetamines.

  36. Can I Drink Alcohol While Taking a Nootropic?

    The broad answer is no, you probably shouldn’t. Alcohol affects just about every system of the body, including the brain and the central nervous system. 

    Nootropics work, in part, by changing the levels of certain chemicals in the brain. Mixing the two could cause unwanted side effects. Some nootropics that have been extensively studied and are prescribed in some European countries have alcohol consumption warnings.

    Piracetam, for example, comes with the warning that you should not consume alcohol while taking it. It’s always good to err on the side of caution. It’s probably not harmful to have a few drinks with most nootropics. But, be aware, that there could be some interactions.

  37. Can I Use Cannabis While Taking a Nootropic?

    Nootropics are drugs that improve memory, focus, attention, and motivation. Cannabis, for most people, has the exact opposite effect.

    By using cannabis with nootropics, you might be canceling out some of the cognitive enhancing effects.

    That being said, mixing cannabis with certain nootropics can enhance other effects.

    Nootropics that affect mood and anxiety levels are often used with cannabis to increase their mood-boosting and anxiety reducing effects.

    Here are a few common nootropic/cannabis combinations.

    Although the use of cannabis and nootropics together has not been scientifically studied, there’s no reason to think that this combination would be dangerous. So, yes, you can use cannabis and nootropics together.

    This combo may increase the mood and anti-anxiety effects of some nootropics. However, it may also diminish the cognitive effects.

  38. Do Nootropics Have Side Effects?

    Side effects from most nootropics are rare. But like all drugs and supplements, nootropics do have potential side effects. These can range from a mild headache to a full-blown allergic reaction. By some definitions, nootropics should not have any serious side effects. And most nootropics seem to be pretty safe for most people.

    But, like anything you put in your body, they can have unwanted results. Some unlikely but possible side effects are:

    – Headaches
    – Anxiety
    – Insomnia
    – Irritability
    – Allergic Reaction

    Allergic reactions are very rare, but they can potentially happen.

    This is true not only of nootropics but of anything you put in your body.

  39. What If I Experience Side Effects?

    If you experience any minor side effects like a mild headache or insomnia, you should discontinue whatever is causing it.

    If your symptoms persist or get worse, see a doctor. If you have an allergic reaction (trouble breathing, extreme anxiety/panic, rapid heartbeat, severe rash), seek professional medical help.

  40. Should Nootropics Be Taken Without Food?

    This will vary from person to person, and from one nootropic to another. Generally, you can take nootropics with or without food. It shouldn’t make much of a difference.

    Some nootropics work best when taken on an empty stomach. Others absorb better with food, specifically fatty foods. Always read the label and see if it is recommended that you take it with food.

  41. Where Can I Read More About Nootropics?

    These are the websites that I started reading on earlier when I was learning about Nootropics.

    I think they are some of the greatest resources:

    Reddit Nootropics, and needless to say,
    Nootropics Information – and our
    blog page.

  42. What are the best or most effective nootropics or smart drugs?

    “Personally, I've been pretty successful with the anti-narcoleptic drug modafinil. It is a wakefulness-promoting agent used in the treatment of narcolepsy and shift work sleep disorder. It's also starting to be used for other disorders, for example as a co-medication for bipolar depression and also ADD. (Note that this is being researched right now. These uses are not officially approved yet.)

    Apart from that, some people do find that using modafinil to enhance productivity, mental clarity and focus – without having any underlying disorder – helps them a great deal in their work life and/or academic pursuits. Simply put, it makes you feel well-rested and it removes any brain-fog you might have from sleep deprivation or (mental) fatigue. It increases your ability to focus and in my experience it helps you to think a lot more systematically. Other than that, the effects are hardly noticeable.

    There is no ‘high' – although new users often experience light euphoria – and therefore modafinil has little to no abuse potential and there is also a very low risk of addiction. Dependence may be an issue for some users though. The effects of modafinil are most obvious when the user is severely sleep deprived. This constitutes one of the biggest potential problems with modafinil. Having wakefulness-promoting medications on hand makes it very easy to deliberately reduce resting hours or to skip a night's sleep entirely, putting your physical and mental well-being at risk.

    Modafinil's effects usually last for six to eight hours. Some users experience a light ‘crash' when the effects wear off, although this is uncommon. Side-effects include headaches (I always keep some painkillers, e.g. ibuprofen, on me when using modafinil.), stiffness or pain in the back and the shoulders, anxiety and agitation. You may also experience changes in your blood pressure and perception. High doses may cause severe restlessness, hallucinations and excessive sweating. In dependent users sudden withdrawals can cause lethargy, extreme fatigue and a lack of motivation.

    Modafinil is a prescription medicine in most countries, which means you need a physician to prescribe it for you.

    For performance enhancement, I recommend using it occasionally for phases in which you need to be highly productive. Long-term use may have serious consequences for your health.

    Overall, modafinil is a powerful supplement for people seeking to enhance their productivity and can be helpful for academic purposes. I'm not sure that I would call it a ‘true' nootropic, but it can certainly be used in the same manner, as it is by many. Being a controlled substance does limit its potential though.“

  43. What are the best nootropics 2019?

    There’s no “one-fits-all” when it comes to the most effective. Different people take nootropics for different reasons.

    Personally, if I were to take one nootropic only for effectiveness, wow, I really can’t just pick one. I think it would be Adrafinil for the stimulation. I’m ADHD, so I already am taking Concerta (extended release Ritalin), and I find Adrafinil to be a very close alternative.

    Sometimes I find it more effective than Ritalin for things like learning and processing new information.

    In terms of best selling to the general public, I remember the list from one of the leading vendors being this:

    Lion’s Mane Mushroom
    Bacopa Monnieri
    – Curcumin Extract

    Generally, if you sort vendors lists by best selling (I just did with Nootropics Depot sorting from best selling), and the top five are:

    Bacopa Monnieri
    Coluracetam (I’m surprised at this one)

  44. What supplements have calming effects?

    Cannabidiol (aka CBD):

    A 2011 study aimed to compare the effects of a simulation public speaking test on healthy control patients and treatment-naive patients with a social anxiety disorder. A total of 24 never-treated patients with a social anxiety disorder were given either CBD or placebo 1.5 hours before the test. Researchers found that pretreatment with CBD significantly reduced anxiety, cognitive impairment and discomfort in their speech performance, and significantly decreased alertness in anticipation of their speech. The placebo group presented stress, anxiety, cognitive impairment and discomfort.

    Agmatine Sulfate:

    Agmatine exhibits antidepressant effects and promotes mood improvement as well as anxiety reduction and relief. It helps the brain and body manage and overcome stress by reducing anxiety and promoting a sense of well-being. By increasing NRF2, agmatine prevents depressive behavior by protecting brain cells from high levels of stress hormone cortisol. Agmatine increases adenylate cyclase in the prefrontal cortex, and decreases levels of adenylate cyclase which associate with depression. Furthermore, it blocks the NMDA receptor, prevents calcium overloading, as well as reverses the decrease of monoamines such as norepinephrine, epinephrine, and dopamine. Depression often associates with a reduction of monoamines in the brain.


    Pramiracetam reports show it improves cognitive deficits associating with traumatic brain injuries. Studies demonstrate and confirm its neuroprotective effects. Studies show that its overall impact on lowering symptoms of depression and anxiety was higher than improving memory. Nevertheless, it was beneficial for both. 

    Bacopa Monnieri

    Bacopa Monnieri is effective in reducing anxiety and stress. Clinical trials show that it significantly decreases anxiety and depression in volunteers, and animal studies compare bacopa to other plant extracts for the effective treatment of anxiety and similar disorders. 


    As an antidepressant and anxiety reliever, Sunifiram produces its effects as a mirror image of an ampakine. It reacts with glutamatergic AMPA receptors. That also allows it to act as a mild stimulant. Sunifiram is known to increase energy and enhance mood. This is likely due to its antidepressant-like effect.


    A review by researchers of a small set of trials concluded that there are benefits of L-theanine in reducing acute stress and anxiety in people with stressful conditions. Oral intake of L-theanine in rats at feasible dosages reduces circulating biomarkers of stress with or without an actual stressor being present. Therefore, it reduces the adverse effects of stress such as memory impairment. Reductions of perceived stress reported in human subjects given oral theanine at the standard dosages. 


    Aniracetam shows strengths in reducing anxiety. Studies show that it affect anxiety by increasing social interactions and improving performance in fear and stress tests. With an increase in serotonin and dopamine, individuals feel a noticeable reduction in anxiety. Thus, becoming a general anxiety relieving agent. Although there are studies that support and verify this process, it is also useful to read personal experiences from Reddit and Longevity communities, where many reports it being far better than Piracetam, Coluracetam, Phenylpiracetam and similar nootropics in the field of anxiety reduction.

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Nootropics Quicklook 2 Nootropics Information

What is ALCAR?

Acetyl-L-Carnitine is a popular multi-functional nutrient, amino acid type nootropic. It benefits the body and brain. A potent antioxidant and neuroprotectant, and a powerful energizing nootropic that promotes anti-aging and longevity.

Acetyl-L-Carnitine Benefits

How to Take
Typical Acetyl-L-Carnitine dosage is 500 mg per day once in the morning, and up to 1,500 mg split into three doses of 500 mg. From there, adjust dosage to your need without exceeding 1,500 mg. At least not during trial period. It is water-soluble, therefore it can be taken with or without food. However, taking ALCAR late in the evening can result in disruption of sleep.
Find the complete research and frequently asked questions on the Acetyl-L-Carnitine page.
What is Adrafinil?
Adrafinil is the pro-drug of Modafinil, and a stimulating nootropic that fights fatigue, increases the brain’s capacity of processing information, boosts energy, as well as enhances subjective well-being. It metabolizes in the body into the widely popular Modafinil (Adrafinil vs Modafinil comparison below). It’s a useful supplement for pulling through long, mentally demanding tasks, learning new topics, or working in shifts as opposed to fixed schedule.
Adrafinil Benefits
How To Take
Adrafinil dosage recommendations vary greatly among different users.
For beginners, start with 300 mg per day and see how your body reacts to it. For a stronger dose, you may take 600 mg.
Maximum allowance per day is 1,200 mg taken in two doses of 600 mg
What is Agmatine Sulfate?
Agmatine is an amino acid that offers a wide of cognitive boosting benefits. It also has excellent effects on reducing neuropathic pain, as well as drug addiction habits. It is neuroprotectant and can reduce tolerance built to many medications like benzodiazepines, morphine, and other painkillers. It also synergizes with SSRI’s & cannabis.
Agmatine Sulfate Benefits
How to Take 
There is currently no standard dosage for agmatine sulfate because there haven’t been enough human studies for determination. These numbers are rough estimates to give an idea of typical, experimental dosing:

For treatment of neuropathic pain: 1,000 to 2,500 mg of agmatine (daily)

For improving cognitive function: 200 to 500 mg of agmatine (daily)

For vasodilation and enhanced recovery: 500 to 1000 mg of agmatine (30 minutes pre-workout)

What is Alpha-GPC?
Alpha-GPC is a natural choline compound. It works on its own as a powerful memory booster. In combination with other nootropics, it works as a potentiator boosting cognitive capabilities. It’s also used as a mild stimulant to boost energy and power output when exercising. Furthermore, it promotes cell regeneration and acts as a neuroprotective agent, against cognitive decline.
Alpha-GPC Benefits
How to Take
Alpha-GPC digests and absorbs smoothly and is gentle on the stomach taken at the typical dose of 300mg. Although many nootropists tend to prefer a dose of 600mg, with a total daily intake ranging from 300 to 1200 mg, either at once or split into two doses. 
Personally I find 300mg is effective enough especially because I almost always take it as part of a stack.
If not Aniracetam then its PiracetamPhenylpiracetam or Noopept.
What is Aniracetam?
Aniracetam is a multipurpose nootropic that provides several benefits. It produces remarkable anxiolytic effects, thereby improving cognition and enhancing mood by ridding anxieties. It also sharpens focus, increases verbal fluency, information processing, as well as expands the brain’s capability of digesting and processing information. Furthermore it produces sense of clarity and well-being.
Aniracetam Benefits
How to take
The best way I found personally was taking one dose (750mg) in the morning and it works the best for me. If necessary, I would take half a dose of noopept 10-15mg later in the day to boost the feeling, but never felt the need of taking more than 1 dose of Aniracetam per day. 
Some people find that splitting Aniracetam into 2 or 3 doses throughout the day works well for them, too. I was never bothered – it seems like too much of a hassle.
But again, everyone has their ways and perfrences. 
To learn more about, check out the Aniracetam documentation
What is Ashwagandha?
Ashwagandha is an excellent herb in Ayurveda medicine. It has become a popular nootropic due to its numerous health benefits. It is able to eliminate stress and anxiety. Research suggest that it helps in improving depression symptoms.
It also increases testosterone levels and significantly boosts sperm quality and fertility in men. Furthermore, it increases muscle mass, reduces body fat and increases strength.
Ashwagandha Benefits
How to Take
Typically, Ashwagandha dose ranges between 300 mg to 600 mg as the highest. Its not advisable to take more than 600mg when using on daily basis. 
Take Ashwagandha with food and divide into two doses per day. If you prefer once a day, do so in the morning after breakfast.
It is not-advisable to use Ashwagandha in combination with JK inhibitors or MAO inhibitors.
What is Bacopa Monnieri?
Bacopa monnieri (also known as Brahmi) is one of the most acknowledged and widely respected nootropics. A traditional Ayurvedic medicine that has a good reputation of being a potent cognitive enhancerstress and anxiety reliever, and brain protector. It improves memory formation and recall speed, it stimulates learning, enhances thought clarity, and increase brain function. It acts as a brain protectant, and studies confirm it as a potential remedy for dementia and similar conditions.
Furthermore, it reduces anxiety and provides a feeling of calm and tranquility, all while eliminating stress. Users report it an excellent relaxant that improves sleep quality, leading to rejuvenating and refreshing rest.
Its nootropic effects are comparable to those of Piracetam, one of the most popular smart drugs in the world. The supplement is produced from the plant extracts.
Bacopa Monnieri Benefits
How To Take 
The minimum effective dose of Bacopa Monnieri is 300mg, taken with food or fat source. Some people, myself included, find it more effective at a higher dosage.
I take 300 to 600mg depending on the purpose, while people like Dave Asprey recommend a daily dose of 750mg.
What is Coluracetam?
Coluracetam is a new member to the racetam family of nootropics. Early scientific trials confirm that it is beneficial in the treatment of Major Depressive Disorder as well as with Generalized Anxiety, in addition to its a bunch of nootropic value it offers.
Coluracetam Benefits
How to Take 
Typically, the recommended starting dose is 20mg due to that being the manufactured one.
There are claims that researchers testing coluracetam dosage of 240 mg per day are finding no side effects. However, the source link to that claim is broken. 
What is L-Theanine?
L-theanine is an amino acid often called the “natural xanax” due to its calming effects. It works by relaxing the body and brain without causing drowsiness, while reducing stress and increasing cognitive function.
Due to not causing drowsiness, it is the perfect choice to combine with stimulants of any sort to take the edge off.

L-Theanine Benefits

Reduces Anxiety & Stress

Improves Memory, Attention, and Cognition

Enhances Sleep Quality

Promotes Longevity and Increases Lifespan

Reduces Symptoms of Depression

Promotes Relaxation without causing Drowsiness

Significantly Reduces Symptoms of Schizophrenia

Enhances Blood Flow and Stimulates Nitric Oxide Production

Reduces Negative Effects of Caffeine & Improves Cognitive Boosting Effects

Additional Benefits

How to Take
The effective l-theanine dose is 200mg. For optimal nootropic results, take l-theanine with caffeine (coffee or supplement, whatever suits you) at a 2:1 ratio. As a stack, it would be:

L-Theanine 200mg

Caffeine 100mg

For those interested, you can actually purchase a supplement pre-made that has 200 mg Theanine & 100 mg Caffeine pressed into one capsule.
What is N-Acetyl-L-Tyrosine?  (NALT)
N-Acetyl L-Tyrosine, often abbreviated to NALT, is a more bioavailable form of L-Tyrosine, an amino acid that also has nootropic benefits. It improves mood, memory, and enhances cognitive abilities in many ways.
It has great effects of reducing stress and maintaining mental performance during sleep deprivation.

What NALT Benefits

Enhances Cognition Under Stress

Improves Memory Under Pressure and Challenges

Increases Dopamine in the Brain and Boosts Cognitive Flexibility

Increases Focus and Supports ADHD Treatment

How To Take
The NALT dosage, however, is lower due to its higher bioavailability. With NALT, the typical daily dosage is 300 mg.
What is Sunifiram?
Sunifiram is an experimental, potent and powerful nootropic that enhances memory, expands learning capacity, and uplifts mood. A recent addition to the racetam family that seems more than promising.
Sunifiram dosage is usually as small as 5 mg due to its potency. And it is yet to be approved anywhere in the world.

Sunifiram Benefits

Reduces Anxiety and Stress

Improves Symptoms of Depression

Enhances Mood and Boosts Energy

Improves Learning Skill and Memory Formation

Enhances Focus and Motivation

Enhances Visual Perception

Increases Libido

How to Take
Sunifiram works effectively at a dosage of 5 to 10 mg –  at a maximum of three times per day.
This is the safe dose which is often taken sublingual for maximum efficacy and absorption.
What is Noopept?
Noopept is one of the most potent nootropics available. It boosts overall cognition with a slight psychostimulatory effect. Effects kick-in within minutes of consumption, making it a handy choice right when dealing with or getting to mentally-demanding tasks.
Noopept Benefits
How to Take
If you prefer to prolong the effect throughout the day, the recommended Noopept dosage would be to take it in three doses of 10mg, or two doses of 15mg, or just one dose of 30mg.

10 mg: divide into three doses throughout the day

15 mg: divide into two doses twice a day

30 mg: one dose per day

Side Effects
These side effects of Noopepts are mostly occurring when higher doses are consumed:


Restlessness (or overstimulation)



Some studies suggest that it magnifies the effects of stimulants such as amphetamines, so caution is advisable for individuals using ADHD medication.
I can personally advise that as well. I’ve felt that sense of overstimulation in a couple different occasion when taking a 30 mg dose of Noopept shortly after taking my ADHD medication.
I now find that a 15 mg dose works best for me whether once or twice per day.
What is Lion’s Mane Mushroom?
Lion’s Mane Mushroom has become one of nature’s most potent nootropic supplement for the brain.
There is evidence that is can permanently enhance brain function as well as protect the brain and promote NGF and neurogenesis.
Lion’s Mane Mushroom Benefits

Enhances Memory and Brain Function

Promotes Nerve Growth Factor and Neuroprotection

Lion Mane Reduces Anxiety and Symptoms of Depression

Reduces Inflammation, Boosts Immunity, and Helps Digestion

Supports Heart and Circulatory System, and Prevents Strokes

Improves Mental Health and Overall Well-Being

How To Take

The lowest effective dosage is 500 mg and the limit per day is 3000 mg. However, higher doses don’t necessarily result in more benefits. A 1000 mg dosage once or twice a day is what I find the most beneficial for my needs.
Side Effects
There are barely any side effects that arise from taking Lion’s Mane. The most common side effect is an itchy skin which is likely due to the increase in Nerve Growth Factor.
It most likely is the cause and could be a good sign that NGF levels are increasing.
What is Piracetam?
Piracetam is a designer nootropic made to enhance brain function.
It’s the primary and original racetam out of all the ones out there today.
Up to date, there has been 20 different derivatives of Piracetam, and counting. It’s a revolutionizing nootropic that improves memory and remarkably boosts cognitive function.

Piracetam Benefits

Improves Memory

Enhances Cognitive Function

Neuroprotective and Prevents Neurodegeneration

Increases Self-Awareness and Promotes Clarity of Thought

Reduces Anxiety, Stress, and Eases Depression

Improves Verbal Learning and Fluency in Dyslexics

Helps with Schizophrenia

How to Take
Typically, the Piracetam dosage for adults is between between 1,200 to 4,800 mg per day.
The most effective Piracetam dose is 1,600 mg. It can be taken once per day, or up to three times per day, totaling a maximum of 4,800 mg per day.
If new to Piracetam and taking it for the first time, start with 1,600 mg and wait and observe your reaction to it.
Few hours later, you can choose whether you want to take another dose, or if one is enough for your needs.
What is Phenibut?
Phenibut is a a GABAergic nootropic that works on the GABA neurotransmitter distinctly reducing anxiety.
It also decreases symptoms of depression, PTSD, improves sleep quality, and gives an overall feeling of ease and well-being.

Phenibut Benefits

Reduces Anxiety & Stress Levels

Increases Sociability

Promotes Sleep Quality

Reduces ADHD Symptoms

Prevents damage to neuronal cells under stress

Enhances Mood and Overall Sense of Ease

How to Take (Dosage)
Start at the lowest effective dose and monitor your response to it, then adjust according to your needs.
A dose of 250 mg is a good starting point for first-timers. Phenibut is a potent compound. 
Don't take it more than twice per week because it builds tolerance quickly.
What is Fasoracetam?
Fasoracetam is a newer addition to the racetam family.
It’s a nootropic that helps in relieving anxiety, enhancing memory, and improving overall cognition.
It’s reported to have the ability to enhance memory and cognition while relieving depression and anxiety.
Additionally, it also has a potential for treating ADHD symptoms.

Fasoracetam Benefits

Improves Memory Cognition

Relieves Anxiety and Depression

Potential ADHD Treatment

Increases Creativity and Motivation

How to Take 
A 20 mg dose is a good starting point. Anecdotal reports testing 20mg and 60mg reported no notable difference.
So more doesn't necessarily mean more effective.
What is Phenylpiracetam?
Phenylpiracetam is a potent and fast-acting racetam type nootropic.
It enhances cognitive abilities and boosts physical strength, stamina, energy, as well as reduces symptoms of depression and anxiety.
Being stimulatory, it is banned by the Olympics Anti-Doping committee to the participating athletes.

Phenylpiracetam Benefits

Improves Cognitive Function, Memory, and Attention

Reduces Anxiety and Depression

Boosts Energy and Increases Physical Mobility

Enhances Physical Performance

How to Take (Dosage)

Typical dose is 100mg for first timers. Take 100mg and see how you feel. After 30 minutes, you can decide if you want to take another 100mg or if it's sufficient. 
Its not recommended to take more than 200mg, and tolerance to it builds quickly.
If you get a headache from taking Phenylpiracetam, then you need to increase choline intake. That can be by eating eggs, for example, or using a choline supplement like Alpha-GPC

Kindly note that the Nootropics UAE webstore has moved to a new website domain and is now accessible on Nootropix

Nootropics UAE


Cash on Delivery

Frequently Asked Questions

We are an e-commerce based store, and our office is based in Abu Dhabi, UAE. However, we don't have a physical store.

To place an order, simply browse to our shop page and choose the products you would like to purchase, add them to your cart, and click on check out.

In most cases when an order is placed before 8 PM, we ship it on the next day. However, if the order is not in stock, it would take between 2 to 3 days instead to be shipped.

Once your order is confirmed we ship it out via a Fetchr courier company. Upon confirmation, you will receive an SMS confirmation as well as your invoice and tracking code via email.

At the moment, we only ship to cities within the UAE: Abu Dhabi, Dubai, Sharjah, Ajman, RAK, and UAQ, as well as Bahrain. But we are on the planning phase of expanding to international shipping.

If you'd like an order that you can't find in our store, you may contact us to request it and we would do our best to add it to the inventory.

If you'd like an order that you can't find in our store, you may contact us to request it and we would do our best to add it to the inventory.

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Frequently Asked Questions

How Long Does Shipping Take?

In most cases where items are in stock and the order is within Abu Dhabi or Dubai, delivery will be on next-day. But even if the product is out of stock, it will always take less than 4 days from confirmation. 

We are also working on a fulfillment service which will allow us to offer next day delivery on all future orders!

What Shipping Methods Do You Use?

We use both Wing (by Amazon), and Fetchr, depending on which one of them can deliver faster at the time of order. 

Once an order is confirmed, the courier picks it up and delivers it door-to-door enclosed. 

An SMS or App notification is sent to you to schedule the delivery location and time that is most convenient to you. Otherwise, the courier will simply call you an hour before they arrive.

How Can I Pay for My Order?

You can pay with Cash on Delivery (COD), PayPal, Credit and Debit Cards. Whichever is more convenient for you.

By default the payment option is Cash on Delivery, however, should you prefer to pay through a credit card, please mention that in the checkout page and an invoice will be generated and send to your email address.

How Much is the Delivery Fee?

All orders within the UAE have a flat rate fee of 30 AED. 

Orders over 500 AED are shipped free of charge, and if you're on the newsletter, we often send out coupons and announce flash-sales. You can sign up to join our mailing list by going to the newsletter page or using the form in the footer. It will also give you a 10% off your first purchase.

When Will X Nootropic Be in Stock Again?

As of now, all our products are also available on backorder. Meaning, if a product you wanted to purchase is out of stock, you can still place an order (backorder) and it will be available with our weekly inventory shipment.

Do You Offer Sample Packets?

If requested, we can arrange a sample order of 3 to 4 different nootropics in a smaller quantity. For example, you can request a racetams sample pack if you aren't sure which one would you prefer. In that case, we will send you a sample packet of your choice.

Typically they are 10 of each: Phenylpiracetam, Pramiracetam, Aniracetam, Noopept, and Oxiracetam.

Of course, they can be changed to your preference in terms of type and quantity.


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